Depression and Simvastatin
“”This is the continuation of my story about Simvastatin (part 8).
HA HA HA! After all I’ve shared with you … who WOULDN’T be depressed for goodness sake? AND just because mental health is my gig doesn’t mean I was immune to this aspect of Simvastatin. Sure, I have had several sad events occur in my life during the past 3 years, and THAT type of situational depression is normal. I knew though that resorting to a life of solitude for as long as I have is not normal and especially so for me because by nature I am a most social animal! For me regarding this depression what was most troubling was the persistent thought that would creep into my head every night for several months. It said, “Just get a butcher knife and cut the damn thing off (my painful left leg) because it’s nothing more than a dead tree stump.” THIS MENTALITY IS NOT ME! I had to FIGHT this thought …. It was so very strong and difficult to control. It made me wonder if this is what suicidal patients struggle fighting with prior to receiving treatment. Hmmmm.
Yes, there is much more to the depression aspect of Simvastatin than the obvious, and here it is ….
“A recent article by You et al calls into question the potentially beneficial effects of statins in the treatment of depression, and even more significantly, the article suggests that statins prescribed for cholesterol reduction may actually cause depression. Since cholesterol plays an important role in neuroprotection, low cholesterol may adversely impact neurotransmission, thereby increasing the risk of depression. Earlier research has demonstrated that patients may be vulnerable to depression, violence, or suicidality during the first month of statin use, with a reduction in risk following that initial period. You et al challenge this contention, stating that depression risk may increase with long-term statin use.”
TBC and if you are interested …
Read the entire article at http://www.empr.com › Features